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Publications and presentations by Jørn Attermann

Peer-reviewed publications 

  1. Handberg, A., Norberg, M., Stenlund, H., Hallmans, G., Attermann, J., Eriksson, J.W. 2010, "Soluble CD36 (sCD36) Clusters with Markers of Insulin Resistance, and High sCD36 Is Associated with Increased Type 2 Diabetes Risk", The Journal of clinical endocrinology and metabolism, 2010;95(4):1939-46.

  2. Nete Hornung, Torkell Ellingsen, Jørn Attermann, Kristian Stengaard-Pedersen, Jørgen Hjelm Poulsen. Patients with rheumatoid arthritis treated with methotrexate (MTX): concentrations of steady state erythrocyte MTX correlate to plasma concentrations and clinical efficacy. Journal of Rheumatology, 2008;35(9):1709-15. .

  3. Hollegaard MV, Grove J, Thorsen P, Wang X, Mandrup S, Christiansen M, Noergaard-Pedersen B, Woejdemann KR, Tabor A, Attermann J, Hougaard DM. Polymorphisms in the tumor necrosis factor alpha and interleukin 1-beta promoters with possible gene regulatory functions increase the risk of preterm birth. Acta Obstetricia et Gynecologica Scandinavica,2008;87(12):1285-90.

  4. Attermann J. An International Normalized Ratio (INR) calibration model which is too simple leads to bias and overestimated accuracy of INR values: a rebuttal. Journal of Thrombosis and Haemostasis, 2007;5(10):2159-60.

  5. Christensen J, Petrenaite V, Attermann J, Sidenius P, Öhman I, Tomson T, Sabers A. Oral contraceptives induce lamotrigine metabolism – evidence from a double blind, placebo controlled trial. Epilepsia, 2007;48(3):484–489.

  6. Møller HJ, Moestrup SK, Weis N, Wejse C, Nielsen HI, Pedersen SS, Attermann J, Nexø E, Kronborg G. Macrophage serum markers in pneumoccocal bacteremia: prediction of survival by soluble CD163. Critical Care Medicine, 2006;34(10):2561-6.

  7. Iversen AKN, Attermann J, Gerstoft J, Fugger L, Mullins JI, Skinhøj P. Longitudinal and cross-sectional studies of HIV-1 RNA and DNA loads in blood and the female genital tract. European Journal of Obstetrics & Gynecology and Reproductive Biology 2004;117:227-35.

  8. Attermann J. Definition of the INR and its consequences for the calibration procedure of thromboplastin preparations: reply to a rebuttal. Journal of Thrombosis and Haemostasis 2004;2:1492-4.

  9. Mølhave L, Kjærgaard SK, Attermann J. Respiratory effects of experimental exposure to office dust. Indoor Air 2004;14:376-84.

  10. Attermann J, Andersen NT, Korsgaard H, Maegaard M, Hasenkam JM. Patient-specific errors in INR agreement between a whole blood coagulometer and a routine plasma based method. Haematologica, 2004;89:504-5.

  11. Attermann J. On the agreement between two diagnostic methods with binary outcomes. Scandinavian Journal of Clinical and Laboratory Investigation 2003;63:525-8.

  12. Attermann J, Andersen NT, Korsgaard H, Maegaard M, Hasenkam JM. Precision of INR measured with a patient operated whole blood coagulometer. Thrombosis Research 2003;110:65-68.

  13. Christensen TD, Andersen NT, Attermann J, Hjortdal VE, Maegaard M, Hasenkam JM. Mechanical heart valve patients can manage oral anticoagulant therapy themselves. European Journal of Cardio-Thoracic Surgery 2003;23:292-8.

  14. Attermann J. Inaccuracy of INR measurements and suggestions for improved WHO guidelines for calibration of reference preparations – a statistical study. Journal of Thrombosis and Haemostasis 2003;1:537-44. 

  15. Iversen AKN, Christiansen CB, Attermann J, Eugen-Olsen J, Schulman S, Berntop E, Ingerslev J, Fugger L, Scheibel E, Tegnborn L, Gerstoft J, Dickmeiss E, Svejgaard A, Skinhøj P. Limited protective effect of the CCR5D32/CCR5D32 genotype on HIV infection incidence in hemophiliacs and selection for genotypic X4 virus. Journal of Infectious Diseases 2003;187:215-25.

  16. Steffensen BF, Hyde SA, Attermann J, Mattson E. Reliability of the EK scale, a functional test for non ambulatory persons with Duchenne dystrophy. Advances in Physiotherapy 2002;4:37-47.

  17. Christensen TD, Attermann J, Hjortdal VE, Maegaard M, Hasenkam JM. Selvstyring af peroral antikoagulationsbehandling hos børn med medfødte hjertesygdomme (Self-management of oral anticoagulant therapy in children with congenital heart disease, in Danish). Ugeskrift for Læger 2002;164:4173-4177.

  18. Mølhave L, Kjærgaard SK, Attermann J, Pedersen OF. Effects in the eyes caused by exposure to office dust. Indoor Air 2002;12:165-74.

  19. Christensen TD, Attermann J, Hjortdal VE, Maegaard M, Hasenkam JM. Self-management of oral anticoagulant therapy in children with congenital heart disease. Cardiology in the Young 2001;11:269-276.

  20. Christensen TD, Attermann J, Pilegaard HK, Andersen NT, Maegaard M, Hasenkam JM. Self-management of oral anticoagulant therapy for mechanical heart valve patients. Scandinavian Cardiovascular Journal 2001;35:107-113.

  21. Mølhave L, Kjærgaard SK, Attermann J. Sensory and other neurogenic effects of exposures to airborne office dust. Atmospheric Environment 2000;34:4755-4766.

  22. Attermann J, Kynde K, Hasenkam JM. Precision of patients’ measurements of the International Normalized Ratio (INR) using a patient operated whole blood home coagulometer. Thrombosis Research 1998;92:287-91.

  23. Hasenkam JM, Kimose HH, Grønnesby H, Andersen NT, Halborg J, Attermann J, Knudsen L, Christensen TD, Pedersen AMH, Lyngbak M, Pilegaard HK. Selvstyring af peroral antikoagulationsbehandling hos patienter med kunstige hjerteklapper (Self-management of oral anticoagulant therapy in patients with artificial heart valves, in Danish with English summary). Ugeskrift for Læger 1998;160:6811-5.

  24. Hasenkam JM, Kimose HH, Knudsen L, Grønnesby H, Halborg J, Christensen TD, Attermann J, Pilegaard HK. Self management of oral anticoagulant therapy after heart valve replacement. European Journal of Cardiothoracic Surgery 1997;11:935-942.

  25. Hasenkam JM, Knudsen L, Kimose HH, Grønnesby H, Attermann J, Andersen NT, Pilegaard HK. Practicability of patient self-testing of oral anticoagulant therapy by the International Normalized Ratio (INR) using a portable whole blood monitor. A pilot investigation. Thrombosis Research 1997;85:77-82.

Other publications

  1.  Attermann J, Andersen NT, Lundbye-Christensen S, Hasenkam JM. Monitoring patients by general state space models. Under preparation for Statistics in Medicine.

  2. Attermann J. Precision of INR measurements by the new CoaguChek S system in the hands of self-managing patients. Research Report no. 2000-3, Department of Biostatistics, University of Aarhus.

  3. Attermann J. Monitoring oral anticoagulant therapy: Measuring coagulant activity. PhD thesis, Faculty of Health Sciences, University of Aarhus 2000. 

  4. Andersen NT, Attermann J, Hasenkam JM, Lundbye-Christensen S, Thomsen HF. Analyse ved hjælp af en state space model af data fra patienter i antikoagulationsbehandling (Analysis by a state space model of data from patients on oral anticoagulant therapy, in Danish). Symposium i Anvendt Statistik 2000;22:1-11.

  5. Attermann J, Lundbye-Christensen S. En oversigt over inferens vha. state space modeller (An overview of inference by state space models, in Danish). Symposium i Anvendt Statistik 2000;22:87-95.

  6. Mølhave L, Kjærgaard SK, Attermann J, Pedersen OF. Husstøv og indeklima. Et klimakammerforsøg med menneskers reaktioner på luftbårent husstøv. Research report (House dust and indoor climate. A climate chamber study on people's reactions to airborne house dust. In Danish with English summary). Department of Environmental and Occupational Medicine, University of Aarhus, 1995.

  7. Attermann J. Longitudinale Data (Analysis of longitudinal data, in Danish). Master's thesis. Department of Mathematical Sciences, University of Aarhus, 1995.

Selected oral presentations (presenter underlined)

  1. Attermann J. Pharmacotherapeutical monitoring of patients on oral anticoagulant therapy by state space models. International Biometric Society, Nordic Regional Conference. Uppsala, Sweden 12-14 June 2003. http://www.bisam.dk/Ultuna_030612.pdf

  2. Christensen TD, Andersen NT, Attermann J, Hjortdal VE, Maegaard M, Hasenkam JM. Mechanical heart valve patients can manage oral anticoagulant therapy themselves.16th Annual Meeting of the European Association For Cardio-Thoracic Surgery. Monaco, 22-25 September 2002.

  3. Attermann J. Estimation of pharmacokinetic parameters in random effects models. Danish Society for Theoretical Statistics, Copenhagen, Denmark, May 2002. http://www.bisam.dk/DSTS_020501.pdf

  4. Christensen TD, Attermann J, Pilegaard HK, Andersen NT, Maegaard M, Hasenkam JM. Selvstyring af peroral antikoagulationsbehandling hos patienter opereret med indsættelse af en mekanisk hjerteklap (Self-management of oral anticoagulant therapy in patients with artificial heart valves). Danish Surgical Society, Copenhagen, Denmark, November 2001.

  5. Christensen TD, Attermann J, Hjortdal VE, Hansen OK, Maegaard M, Hasenkam JM. Børn og selvstyret AK-behandling (Children and self-managed oral anticoagulant therapy). Danish Society on Thrombosis and Haemostasis. Hvidovre, Denmark, 27 September 2001.

  6. Attermann J. Kvalitetsvurdering af antikoagulationsbehandling (Evaluation of quality of oral anticoagulant therapy). Symposium arranged by Roche Diagnostics A/S, Copenhagen and Aarhus, Denmark, 21-22 August 2001.

  7. Christensen TD, Attermann J, Hjortdal VE, Hansen OK, Maegaard M, Hasenkam JM. Selvstyring af peroral antikoagulationsbehandling hos børn opereret for medfødte hjertesygdomme (Self-management of oral anticoagulant therapy in children operated for congenital heart disease). Danish Surgical Society. 18-19 April 2001.

  8. Attermann J. Quality assessment of self managed oral anticoagulant therapy. Nordic meeting on Self Monitoring and Self Management of Oral Anticoagulant Therapy. Aarhus, Denmark, 28 February – 1 March 2001.

  9. Mølhave L, Kjærgaard SK, Attermann J. Sensory and other neurogenic effects of exposures to airborne office dust. Healthy Buildings 2000, Espoo, Finland, 6-10 August 2000.

  10. Maegaard M, Christensen TD, Attermann J, Andersen NT, Kimose HH, Pilegaard H, Hasenkam JM. Selvstyring af oral antikoagulationsbehandling for patienter med indopereret mekanisk hjerteklap – 4 års opgørelse (Self-management of oral anticoagulant therapy in patient with artificial heart valves - 4 years foolow-up). Danish Society for Thoracic Surgery. København, 26 May 2000.

  11. Attermann J. Kvalitet af INR-målinger (Quality of INR measurements). Invited expert. Aalborg Sygehus, 1 May 2000.

  12. Attermann J. Institut for Biostatistik og dets kvalifikationer (Department of Biostatistics and its qualifications). Center for Clinical Pharmacology and Department of Clinical Biochemistry, Århus Kommunehospital,Aarhus, Denmark, 25 April 2000.

  13. Christensen TD, Attermann J, Andersen NT, Maegaard M, Kimose HH, PilegaardHK, Hasenkam JM. Self management of oral anticoagulation therapy for mechanical heart valve patients – 4 years of experience. 10th Annual Meeting of the Scandinavian Society for Research in Cardiothoracic Surgery. Geilo, Norway, 10-13 February 2000.

  14. Andersen NT, Attermann J, Hasenkam JM, Lundbye-Christensen S, Thomsen HF. Analyse ved hjælp af en state space model af data fra patienter i antikoagulationsbehandling. (Analysis by a state space model of data from patients on oral anticoagulant therapy). 22. Symposium on Applied Statistics, Aalborg, Denmark, 24-25 January 2000.

  15. Attermann J, Lundbye-Christensen S. En oversigt over inferens ved hjælp af state space modeller. (A review of inference by state space models) 22. Symposium on Applied Statistics, Aalborg, Denmark, 24-25 January 2000.

  16. Om selvstyring af AK-behandling. Univers, TV2/Nord, 24. oktober 1999.

  17. Christensen TD, Attermann J, Pilegaard HK, Andersen NT, Maegaard M, Hasenkam JM. Self management of oral anticoagulant therapy for mechanical heart valve patients – 4 years follow-up. The Anticoagulation Forum, Vancouver, Canada, 13-15 May 1999.

  18. Attermann J, Andersen NT. Effect of calibration errors on estimates of the international normalized ratio (INR). 4. Danish Congress on Clinical Biochemistry, Esbjerg, Denmark, 6-7 May 1999.

  19. Attermann J, Kynde K, Hasenkam JM. Precision of International Normalized Ratio (INR) measurements using a patient operated whole blood coagulometer. 9th Annual Meeting of the Scandinavian Society for Research in Cardiothoracic Surgery. Geilo, Norway, 4-10 February 1999.

  20. Christensen TD, Hjortdal VE, Attermann J, Hansen OK, Sørensen K, Maegaard M, Hasenkam JM. Self management of oral anticoagulant therapy in children with congenital heart disease – a descriptive study with up to 1 year follow-up. 9th Annual Meeting of the Scandinavian Society for Research in Cardiothoracic Surgery. Geilo, Norway, 4-10 February 1999.

  21. Hasenkam JM, Attermann J, Andersen NT, Christensen TD, Maegaard M, Pilegaard H. Patient Regulated or Monitored Oral Anticoagulant Therapy (PROMOAT). New Era Cardiac Care: Innovation and Technology. Scottsdale, Arizona. 7-10 January 1999.

  22. Hasenkam JM, Attermann J, Christensen TD, Andersen NT, Kimose HH, Grønnesby H, Pilegaard H. Better prevention of thromboembolic events by self managed oral anticoagulant therapy (SMOAT). Workshop on Prosthetic Heart Valves: Future Technologies. Georgia Institute of Technology, Atlanta, USA. 18 - 22 February 1998.

  23. Attermann J, Andersen NT, Hasenkam JM, Nielsen JD, Pilegaard HK. Monitoring patients on oral anticoagulant therapy - a preliminary sketch. Swedish-Danish symposium on longitudinal analysis, Gl. Vrå Slot, Denmark, 9-10 December 1997.

  24. Christensen TD, Hasenkam JM, Attermann J, Andersen NT, Kimose HH, Grønnesby H, Pilegaard HK. Self management of oral anticoagulation treatment in heart valve patients - up to 2 years follow-up. SATS & SCANSECT, Trondheim, Norway, 20-22 August 1997.

  25. Attermann J, Hasenkam JM, Andersen NT, Grønnesby H, Pilegaard HK. Precision of the International Normalized Ratio (INR) measured by a patient operated home coagulometer. Skejby Sygehus, Aarhus, Denmark, 17. September 1997.

  26. Attermann J, Andersen NT, Hasenkam JM, Nielsen JD, Pilegaard HK. Overvågning af patienter i peroral antikoagulationsbehandling - statistiske overvejelser. (Monitoring patiens on oral anticoagulant therapy - statistical considerations). The Cardiovascular Research Center, Aarhus University, Aarhus, Denmark, May 1997.

  27. Attermann J, Hasenkam JM, Andersen NT, Knudsen L, Kimose HH, Grønnesby H, Pilegaard HK. Patient self-management of oral anticoagulant therapy - some statistical considerations. Scandinavian Society for Research in Cardiothoracic Surgery, 7th Annual Meeting, Geilo, Norway, 6-9 February 1997.

 Selected poster presentations (presenter underlined)

  1. Handberg, A., Norberg, M., Stenlund, H., Attermann, J., Eriksson, J. 2009, "Soluble CD36 may be an early insulin resistance marker of the metabolic syndrome", fremlagt ved 3rd International congress on prediabetes and the metabolic syndrome, Nice, 1.4.2009 - 4.4.2009.

  2. Tvedegaard KC, Parner E, Attermann J, Hooper CW, Gregersen N, Hollegaard MV, Hougaard D, Thorsen P. Genetic markers for development of autistic disorder based on multiplex genotyping. INTERNATIONAL MEETING FOR AUTISM RESEARCH 6, Seattle, USA, 3-5 May 2007.

  3. Tvedegaard KC, Parner E, Hooper CW, Attermann J, Gregersen N, Thorsen P. Multiplex SNP analysis on whole genome amplified DNA from archived dried bloodspots, a validation study. Planet xMap, Los Angeles, USA, 12-14 March 2007.

  4. Hollegaard MV, Grove J, Thorsen P, Wang X, Mandrup S, Christiansen M, Nørgaard-Petersen B, Schendel DE, Wøjdemann KE, Tabor A, Attermann J, Hougaard DM. Cytokine SNPs associated with Preterm Birth. 6th International Cytokine Conference 2006. Hilton-Stadtpark, Vienna, Austria, August 27-31, 2006.

  5. Christensen J, Jørgensen E, Attermann J, Sidenius P, Poulsen JH. Hyponatremia during oxcarbazepine therapy correlates with serum levels. Danish Pharmacology 2003. Odense, Denmark, 22 January 2003.

  6. Christensen TD, Andersen NT, Attermann J, Hjortdal VE, Maegaard M, Hasenkam JM. Self-management of oral anticoagulant therapy - performance and assessment of thromboembolic and bleeding complications in 254 patients. Sixth Annual Hilton Head Workshop, Hilton Head Island, South Carolina, USA, 6-10 March 2002.

  7. Lauridsen AL, Heinsvig EM, Poulsen PL, Attermann J, Poulsen JH. Revision af referenceintervaller for Pt(U)-Adrenalin, Pt(U)-Noradrenalin og Pt(U)-Vanillinmandelat (Revision of reference intervals for Pt(U)-Adrenalin, Pt(U)-Noradrenalin og Pt(U)-Vanillinmandelat). 5th Danish Congress on Clinical Biochemistry. Vejle, Denmark, 25-26 October 2001.

  8. Attermann J. Overestimated accuracy of the International Normalized Ratio (INR) leads to conflicting results in clinical trials and in management of oral anticoagulant therapy. XVIIIth Congress of International Society on Thrombosis and Haemostasis (ISTH). Paris, France, 6-12 July 2001.

  9. Christensen TD, Attermann J, Hjortdal VE, Hansen OK, Maegaard M, Hasenkam JM. Children with congenital heart disease can perform self-management of oral anticoagulant therapy. XVIIIth Congress of International Society on Thrombosis and Haemostasis (ISTH). Paris, France, 6-12 July 2001.

  10. Attermann J. Accuracy of the International Normalized Ratio (INR) may be seriously overestimated due to unrealistically strong assumptions in the guidelines published by the World Health Organization. Euromedlab 2001, 14th IFCC-FESCC European Congress of Clinical Chemistry and Laboratory Medicine. Praha, Czech Republic, 26-31 May 2001.

  11. Christensen TD, Attermann J, Hjortdal VE, Maegaard M, Hasenkam JM. Self-management of oral anticoagulant therapy in children with congenital heart disease. 49th Annual Meeting of the Scandinavian Association for Thoracic Surgery (SATS). Linköping, Sweden, 24-26 August 2000.

  12. Andersen NT, Attermann J, Hasenkam JM, Lundbye-Christensen S, Thomsen HF. Application of State-Space Models and Monte Carlo Methods for Analyzing Longitudinal Data from Patients on Anticoagulant Therapy. 6th World Meeting of the International Society for Bayesian Analysis (ISBA), Heraklion, Crete, Greece, 28 May – 1 June 2000.

  13. Andersen NT, Attermann J, Hasenkam JM, Lundbye-Christensen S, Thomsen HF. Application of State-Space Models and Monte Carlo Methods for Analyzing Longitudinal Data from Patients on Oral Anticoagulant Therapy. Second European Conference on Highly Structured Stochastic Systems (HSSS), Pavia, Italy, 14-18 September 1999.

  14. Attermann J, Kynde K, Hasenkam JM. Are portable coagulometers adequate for patient self management of oral anticoagulant therapy? Featured poster, XVIIth Congress of International Society on Thrombosis and Haemostasis (ISTH), Washington DC, USA, 14-21 August 1999.

  15. Christensen TD, Hjortdal VE, Attermann J, Hansen OK, Sørensen K, Maegaard M, Hasenkam JM. Patient regulated or monitored oral anticoagulant therapy (PROMOAT) in children with congenital heart disease – a feasibility study. XVIIth Congress of International Society on Thrombosis and Haemostasis (ISTH), Washington DC, USA, 14-21 August 1999.

  16. Hasenkam JM, Attermann J, Christensen TD, Andersen NT, Kimose HH, Grønnesby H, Pilegaard HK. Better prevention of thromboembolic events by self managed oral anticoagulant therapy. Workshop on Prosthetic Heart Valves: Future Technologies, Hilton Head, S.C., USA. 18-22 February 1998.